But is a chronic bladder pain syndrome present

Interstitial cystitisInterstitial cystitis is a special form of cystitis. Also known as chronic bladder pain syndrome, this is a chronic condition of the urinary bladder. It is caused by inflammation of the urinary bladder wall. The signs are initially the same as those of a common bladder infection, but the symptoms of interstitial cystitis are much more severe and varied. In addition, the fluctuating course of the disease is characteristic of chronic bladder pain syndrome. The biggest difference to recurrent cystitis is that interstitial cystitis is not caused by bacteria. A diagnosis and therapy options are thus made more difficult. In any case, the clinical picture confronts many physicians with a riddle, the origin is still largely unclear today. In principle, the disease can affect anyone, but as in the case of cystitis, it is mostly women who suffer from it.

Symptoms of interstitial cystitis

Those who suffer from interstitial cystitis usually complain of the same symptoms as those typical of acute cystitis: a frequent urge to urinate and burning when urinating. However, in the case of chronic bladder pain syndrome, the symptoms are extremely severe. Patients have to visit the toilet up to 60 times a day. Pain in the bladder or genital region often radiates to the entire abdomen. May occur in association with cramps, both when going to the toilet and at any other time.

Typical symptoms for interstitial cystitis also include:

– Muscle and joint pain – Gastrointestinal problems – Chronic pelvic pain – Permanent feeling of prere on the urinary bladder

Patients also complain of migraines or allergies, and often also suffer from autoimmune diseases such as rheumatoid arthritis or lupus erythematosus. Due to the extreme symptoms, sufferers are severely restricted in their everyday lives. In addition to the typical signs of the disease, sufferers therefore more frequently suffer from depressive moods and social isolation.


In any case, interstitial cystitis is a very rare disease that has not yet been fully researched. Even clear causes can therefore not be identified by physicians to this day. The only thing that is certain is that, unlike a common bladder infection, it is caused without the involvement of bacteria.

Experts discuss previous infections, toxic substances, and hormonal or neurological disorders as possible causes. What is also clear is that the urinary bladder wall plays a crucial role. A possible trigger is considered to be a change in the permeability of the bladder. If the bladder mucosa is more permeable, aggressive components of the urine, for example, can penetrate deeper into the bladder wall and cause chronic inflammation.

In addition, those affected often also fight allergies or autoimmune diseases. If this is the case, the body considers its own tie to be an intruder that must be fought against. The result: an inflammatory reaction. If the mucous membrane of the bladder is affected, pathogens have an easy time of it. This is also the reason why people suffering from interstitial cystitis sometimes additionally fight against acute cystitis caused by bacteria.

Another amption is that lack of oxygen in the pelvic area can be a trigger for interstitial cystitis.


It is extremely difficult to detect interstitial cystitis. A final diagnosis is made according to the principle of exclusion. A visit to a specialist is often necessary.

A diagnosis is so challenging because other diseases in which affected individuals have similar symptoms must first be ruled out. In further examinations, the attending physician can detect bleeding or tears in the bladder mucosa with the help of a bladder examination – an indication that interstitial cystitis could be present. Patients are also often asked to keep a pain and micturition diary in order to document their toilet trips accurately.

Treat interstitial cystitis

A form of therapy that combats the causes is currently unknown. Instead, physicians rely on individualized treatment methods that are tailored to the specific patient. The main aim of the therapy is to reduce the symptoms and improve the quality of life. The goal is to rebuild the bladder wall.

In addition, medication can be administered, for example to relieve pain. Bladder irrigation can also help – but is only used occasionally, as there is also a risk of infection.


Femannose ® N with the ingredient D-mannose is used for the prevention and supportive treatment of cystitis and is suitable for people over 14 years of age. The active ingredient D-mannose neutralizes inflammation-causing E.coli bacteria, which are then flushed out with the urine.

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