Drug-food interactions

Drug-food interactionsSome combinations of foods and drugs cause the drugs to not work to their full potential. Others may cause unwanted. Sometimes cause dangerous side effects. You can read about which foods this can be in combination with which medications here.

drug-food interactions

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Note: This list contains only a part of all possible interactions between food and drugs and can not replace an individual consultation with a doctor or pharmacist. Ideally, medications should be taken with a glass of water. How to avoid interactions at all costs.

At a glance:

High-fiber foods

Foods rich in fiber, such as muesli, whole grain bread, or legumes, can delay the absorption of pain medications into the bloodstream. For this reason, in order to achieve a quick effect, high-fiber foods should be avoided for about two hours before and after taking the medication.

Drug-food interactions

Fruit juices and other drinks containing citrate

Fruit juices and other drinks containing citrates, such as lemonade or wine, can cause confusion and seizures when combined with antacids that contain aluminum salts. The reason for this is that aluminum is absorbed into the bloodstream much more easily and quickly in the presence of citrate. A time interval of two hours between taking medication. It is therefore advisable not to consume beverages containing citrate.

Grapefruits and grapefruit juice

Grapefruit and grapefruit juice can interact with various medications. Antihistamines are used to treat allergies. Can trigger cardiac arrhythmias when combined with substances from grapefruit. Anyone taking antihistamines should therefore avoid the sour fruit altogether from their diet.

calcium antagonists to lower blood prereGrapefruit and grapefruit juice can prevent the degradation of calcium antagonists used to lower blood prere and thus intensify their effect. Possible consequences are a sharp drop in blood prere and dizziness, which is why grapefruits and their juice should be avoided during treatment with such drugs.

Painkillers and grapefruit: Some painkillers can cause cardiac arrhythmias when combined with ingredients in grapefruit. Therefore, grapefruit should not be consumed two hours before and after taking medication.

Sleeping pills and grapefruit: The effect of some sleeping pills can be amplified many times by certain ingredients of grapefruit, so that alcohol intoxication-like symptoms are possible. It is therefore advisable to avoid grapefruits and grapefruit juice two hours before and after taking sleeping pills.

Statins and grapefruitStatins are cholesterol-lowering drugs, some of which, when combined with grapefruit substances, can cause muscle weakness, pain, fatigue, and fever. Therefore, grapefruit or grapefruit juice should not be eaten or drunk during therapy with statins such as simvastatin.

Dr. Heart / Expert Team

Coffee and caffeinated drinks

Caffeinated beverages such as coffee or cola should be avoided in combination with certain groups of medications.

Iron supplementsIron preparations can be weakened in their effect by the tannins contained in coffee. Because the tannins, which may also be contained in tea or wine, combine with the iron and clump it together so that it cannot enter the bloodstream. For this reason, coffee and other drinks containing tannins should be drunk only at a distance of about two hours from the time when iron supplements are taken.

Gyrase inhibitors and caffeineGyrase inhibitors are drugs that are used to treat kidney or bladder infections. Since these substances are broken down in the body by the same mechanism as caffeine, the caffeine remains in the bloodstream longer and can thus cause heart palpitations or sleep disturbances. Therefore, caffeine should generally be avoided during treatment with gyrase inhibitors such as ciprofloxacin, enrofloxacin or nalidixic acid.

TheophyllineTheophylline is a drug commonly found in medications for respiratory diseases such as asthma. This substance has a similar effect to caffeine. Is therefore additionally intensified by coffee or cola. For this reason, it is recommended not to consume caffeine while taking theophylline-containing medications.

Licorice and diuretics

Liquorice contains high amounts of glycyrrhizic acid, which can have a significant effect on the body's sodium and potassium balance if consumed in excess. This is particularly problematic in connection with diuretics, as salts are increasingly excreted along with the water. Thus, licorice in combination with dehydration preparations can easily lead to a potassium deficiency, which manifests itself, among other things, through fatigue, muscle weakness or increased blood prere.

Milk/dairy products and antibiotics

Milk and dairy products such as cheese, yogurt, or cottage cheese can reduce the effectiveness of certain antibiotics (tetracyclines and quinolones). Because the calcium contained binds the active substances. Prevents absorption via the small intestine into the bloodstream. Therefore, milk and dairy products should not be consumed for about two hours before and after taking corresponding medications. This applies, for example, to the drugs doxycycline and minocycline as well as ciprofloxacin and norfloxacin. Contrary to popular belief, penicillin and many other antibiotics do not interact with milk. However, these preparations should also not be taken at the same time as milk to avoid intolerance reactions.

Minerals and food supplements

Minerals such as calcium, magnesium or iron can reduce the effect of a variety of drugs or lead to undesirable side effects. An example of this is the attenuating effect of calcium. Magnesium on various antibiotics. Anyone who regularly takes mineral supplements or drinks mineral water that is very rich in minerals should therefore always clarify possible interactions with medications with a doctor or pharmacist.

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