What is Equine Cushing Syndrome?? The Cushing syndrome, also Equine Cushing Syndrome (ECS) is an incurable disease Disease, which are Metabolic disorder expresses. This leads to problems in the Coat change, which is why affected horses in most cases have a very long coat. In addition to this main symptom, often occur Laminitis and muscle atrophy as further unpleasant accompanying symptoms.
What is the cause of Cushing's Syndrome?
Cells responsible for the production of the neurotransmitter dopamine die more easily in Cushing's horses. This dysfunction triggers a negative sequence of hormonal events in the brain.
Due to the death of the cells, less dopamine is produced, which reduces the activity of the so-called "dopamine" Pituitary gland getting out of control. The dopamine deficit leads as a result to a massive enlargement of the pituitary gland, which in some cases can be the trigger for tumors to appear.
When the unchecked hormone ACTH reaches the adrenal cortex, it boosts the production of the stress hormone cortisol. The horse has an elevated blood glucose level. The immune system is weakened. Also a longer administration of cortisone can be a trigger for Cushing's disease.
How does the Cushing's syndrome appear in horses??
Which horses are affected? Cushing's is a typical disease of old age. Occurs therefore more often in horses from the age of 15. of life (20% of the horses in the Age of 15+). The frequency of the disease increases with age, so that up to 95% of horses around the age of 30 are affected by Cushing's disease. What are signs. Symptoms of Cushing's syndrome?
The disease generally begins insidiously and it can take years before the typical symptoms become apparent Symptoms express. In the early stages of the disease, Cushing's is manifested by apathy, profuse sweating and rapid fatigue of the horse.
The surest and at the same time most obvious sign is the disturbance of the coat metabolism, which results in unnaturally thick and long coats even in the summer months. Since horses affected by Cushing's often have a malfunction of the sugar metabolism, they can be prone to hoof ulcers due to the resulting insulin resistance. Further consequences can be infertility of the horse, as well as an accumulation of fat deposits on the horse's body.
In the advanced stage, the following complaints may occur:
– Increased susceptibility to infections – Muscle atrophy – Wound healing disorders – Kidney dysfunction, which leads to increased water intake and more frequent urination laminitis
Muscle atrophy as a frequent accompanying symptom
How to treat Cushing's syndrome?
The incurable Equine Cushing's Syndrome is diagnosed very reliably by means of ACTH measurement. If the positive finding is present, the Therapy Start immediately, as early detection and treatment is associated with good chances of success.
Despite the fact that Cushing's is an incurable disease, the quality of life of the horse can be improved by targeted Medication or. restore. Particularly successful in the treatment of Cushing's is the active ingredient Prascend, which is administered to the horse on a daily basis for the rest of its life. Prascend stimulates dopamine production, which causes the pituitary gland to stop producing excessive hormones.
In order to maintain the horse's quality of life, it is recommended that the horse be seen regularly by the veterinarian, as the dose of the administered drug must be adjusted over time in most cases.
Monk's pepper can be given to the horse as a dietary supplement to support this.
How to prevent Cushing's in horses?
In order to minimize the outbreak of Cushing's disease, a species-appropriate husbandry with plenty of room to move is recommended. Regular exercise, which is so important to avoid obesity and stress; two factors that also promote the onset of Cushing's disease.
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